Lyme disease is a bacterial infection, transmitted by the bite of an infected tick.  Early diagnosis and treatment provides the best chance of recovery, but symptoms can be non-specific and easily missed at all stages, with potential long term debilitating consequences.  This session will provide insight into the wide array of Lyme disease symptoms, that may present in primary care, highlight the key advice within the NICE Lyme Disease Guideline (NG95), present results from a recent UK national survey of patient experiences and include case study to demonstrate the consequences of a delayed diagnosis. LEARNING OUTCOMES At the end of the session participants will be able to:  Recognise the signs and symptoms of early and disseminated Lyme disease.  Know how to differentiate ‘erythema migrans' rashes from other insect bites or rashes. Understand the importance of early and adequate antibiotic treatment in preventing persistent symptoms.  Know where to access up-to-date educational material and guidelines on Lyme disease.  More confidently advise on tick bite prevention & correct use of tick removers.  Outline the potential role of the nurse practitioner in developing ‘Lyme Awareness' across the primary care team.  Have an awareness of the recognised scientific uncertainties and the need for further research.